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NASDAQ: SUPN SUPERNUS PHARMACEUTICALS, INC. 8-K

Supernus reports 39% Q1 revenue growth to $207.7M, driven by ZURZUVAE and ONAPGO

Filed May 5, 2026 · Period ending May 5, 2026 · ~1 min read

5 key changes 3 high relevance 2 sections

Key Changes

  • high

    Q1 2026 revenues rose 39% year-over-year to $207.7M, driven by 56% growth in four key products (Qelbree, GOCOVRI, ZURZUVAE, ONAPGO) to $149.1M and a $20M Shionogi commercial milestone.

    Item 2.02 — Results of Operations and Financial Condition verify on EDGAR →
  • high

    ZURZUVAE collaboration revenue reached $27.6M (50% of Biogen's net revenues); Biogen reported U.S. sales doubled year-over-year and total prescriptions increased 82%.

    Exhibit 99.1 view on EDGAR →
  • high

    Company reaffirmed full-year 2026 guidance: $840-870M total revenues, $0-30M operating earnings, and $140-170M adjusted operating earnings.

    Exhibit 99.1 view on EDGAR →
  • medium

    ONAPGO generated $8.4M in Q1 sales after resuming new patient starts in February; company plans Q3 2026 FDA filing for second supplier with potential mid-2027 approval to address supply constraints.

    Exhibit 99.1 view on EDGAR →
  • medium

    Shionogi collaboration delivered a one-time $20M commercial milestone, contributing to 274% increase in royalty and licensing revenues to $29.3M.

    Exhibit 99.1 view on EDGAR →

Summary

Supernus delivered strong first-quarter results with 39% revenue growth to $207.7 million, demonstrating momentum across its growth portfolio. The standout performer was ZURZUVAE, the postpartum depression treatment co-marketed with Biogen, which doubled U.S. sales year-over-year and contributed $27.6 million in collaboration revenue to Supernus.

ONAPGO, the company's Parkinson's disease psychosis treatment, resumed new patient initiations in February after supply constraints and generated $8.4 million in Q1 sales, with over 645 prescribers submitting enrollment forms since launch. The quarter also included a $20 million one-time commercial milestone from Shionogi, boosting licensing revenues.

Operating losses narrowed to $8.3 million from $10.3 million a year earlier. Management reaffirmed full-year 2026 guidance of $840-870 million in revenues and $140-170 million in adjusted operating earnings, signaling confidence in the growth trajectory. The planned Q3 2026 FDA filing for a second ONAPGO supplier addresses a key operational risk, with potential approval by mid-2027 to support expanded patient access.

Section-by-Section Diff

Event · Item 2.02 — Results of Operations and Financial Condition

~500 words

Supernus announced Q1 2026 financial results via press release and conference call on May 5, 2026.

1 Added
Added Q1 2026 earnings announcement high

Added in current filing · verify on EDGAR →

On May 5, 2026, Supernus Pharmaceuticals, Inc. (“Supernus” or the “Company”) issued a press release regarding its financial results for the first quarter ended March 31, 2026.

The company disclosed its first quarter 2026 financial results through a press release. The 8-K itself does not contain the actual financial figures — those are in the attached press release exhibit. The company also hosted a conference call on the same day to present business and financial results.

Event · Exhibit 99.1

3 Added
Added Q1 2026 earnings high

Added in current filing · view on EDGAR →

Total revenues were $207.7 million in the first quarter 2026, a 39% increase compared to same period last year.

Supernus reported total revenues of $207.7 million for Q1 2026, up 39% year-over-year from $149.8 million. The growth was driven by a 56% increase in combined revenues from four growth products (Qelbree, GOCOVRI, ZURZUVAE, ONAPGO) to $149.1 million, plus a $20 million commercial milestone from Shionogi. Operating loss narrowed to $8.3 million from $10.3 million in Q1 2025.

Added ONAPGO second supplier filing medium

Added in current filing · view on EDGAR →

Regulatory submission to the FDA for second supplier for ONAPGO expected in third quarter 2026, with potential approval by mid-year 2027.

Supernus plans to file a regulatory submission to the FDA for a second supplier for ONAPGO in Q3 2026, with potential approval by mid-2027. This addresses supply constraints that paused new patient initiations; ONAPGO resumed new patient starts in February 2026 and generated $8.4 million in Q1 2026 net sales. Approximately 2,200 enrollment forms have been submitted by over 645 prescribers since the April 2025 launch.

Added Full year 2026 guidance reiterated high

Added in current filing · view on EDGAR →

For the full year 2026, the Company reiterates its full year financial guidance as set forth below (dollars in millions): Current Guidance (as of February 24, 2026) Total revenues include the following(7): ◦ONAPGO net sales of $45 million - $70 million ◦Trokendi XR and Oxtellar XR net sales of $40 - $50 million $840 - $870 Combined R&D and SG&A expenses $620 - $650 Operating earnings $0 - $30 Adjusted operating earnings (non-GAAP) (1) $140 - $170

Supernus reiterated its full-year 2026 guidance: total revenues of $840-870 million (including ONAPGO net sales of $45-70 million and Trokendi XR/Oxtellar XR net sales of $40-50 million), combined R&D and SG&A expenses of $620-650 million, operating earnings of $0-30 million, and adjusted operating earnings (non-GAAP) of $140-170 million.

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Figures/quotes linked to EDGAR · Narrative written by AI · Jun 19, 2026 · How we verify