NASDAQ: SPTX

Seaport Therapeutics, Inc.

CIK 0002042347 · SIC 2834 · Pharmaceutical Preparations

Small by assets Assets $442M as of Aug 30, 2026

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10-Q Filed Aug 3, 2026 · Period ending Jun 30, 2026

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8-K Filed Aug 3, 2026 · Period ending Aug 3, 2026

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10-Q Filed Jun 8, 2026 · Period ending Mar 31, 2026

net income -$25.4M. Seaport Therapeutics debuts with IPO, advancing two neuropsychiatric trials

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8-K Filed Jun 8, 2026 · Period ending Jun 8, 2026

Seaport Therapeutics reports Q1 2026 financial results

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8-K Filed May 4, 2026 · Period ending May 4, 2026

Seaport Therapeutics completes IPO, Class A common stock capital structure (full multi-class details, if any, are in the charter exhibit / prospectus — not disclosed in this filing body) with 700M shares

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Latest financial statements

From 10-Q filed Aug 3, 2026 (period ending Jun 30, 2026). As printed on the EDGAR/iXBRL face — not generated by the model.

As filed

Condensed Consolidated Statements of Operations and Comprehensive Loss (Unaudited)

(In thousands, except share and per share amounts)

Description Three months ended June 30, 2026 Three months ended June 30, 2025 Six months ended June 30, 2026 Six months ended June 30, 2025
Operating expenses:
Research and development (including non-cash stock-based compensation expense of $0.9 million and $0.6 million for three months ended June 30, 2026 and 2025, respectively and $1.8 million and $1.1 million for six months ended June 30, 2026 and 2025, respectively) 24,619 13,409 46,049 23,944
General and administrative (including non-cash stock-based compensation expense of $36.0 million and $1.2 million for three months ended June 30, 2026 and 2025, respectively and $37.6 million and $2.3 million for six months ended June 30, 2026 and 2025, respectively) 41,189 5,061 47,302 10,711
Total operating expenses 65,808 18,470 93,351 34,655
Loss from operations (65,808) (18,470) (93,351) (34,655)
Other income (expense), net
Interest income, net 3,257 2,976 5,390 6,076
Research and development tax credit 236 610 803 610
Other expense, net (34) (59) (80) (68)
Total other income, net 3,459 3,527 6,113 6,618
Loss before income taxes (62,349) (14,943) (87,238) (28,037)
Income tax provision 251 134 770 165
Net loss (62,600) (15,077) (88,008) (28,202)
Other comprehensive income (loss), net of tax:
Foreign currency translation adjustment 18 (3) 33 (3)
Unrealized (loss) gain on available-for-sale securities (557) (59) (809) 133
Comprehensive loss (63,139) (15,139) (88,784) (28,072)
Net loss per share, basic and diluted (1.78) (6.40) (4.60) (12.05)
Weighted-average common shares outstanding, basic and diluted 35,236,214 2,356,777 19,118,049 2,340,431

Condensed Consolidated Balance Sheets (Unaudited)

(In thousands, except share and per share amounts)

Description June 30, 2026 December 31, 2025
Assets
Current assets:
Cash and cash equivalents 64,223 46,042
Short-term investments 209,086 169,941
Prepaid expenses and other current assets 8,866 7,247
Total current assets 282,175 223,230
Property and equipment, net 360 412
Right-of-use assets operating leases 4,741 4,813
Long-term investments 153,951 17,670
Other non-current assets 454 2,884
Total assets 441,681 249,009
Liabilities, convertible preferred stock and stockholders' equity (deficit)
Current liabilities:
Accounts payable 5,705 2,007
Related party payable 7
Accrued expenses and other current liabilities 8,358 9,131
Operating lease liability 1,611 1,637
Total current liabilities 15,674 12,782
Operating lease liability, net of current portion 3,405 3,444
Total liabilities 19,079 16,226
Series A-1 convertible preferred stock, par value $0.0001; zero and 40,000,000 shares authorized as of June 30, 2026 and December 31, 2025, respectively; zero and 40,000,000 shares issued and outstanding as of June 30, 2026 and December 31, 2025, respectively; liquidation preference of zero and $4,000 as of June 30, 2026 and December 31, 2025, respectively
Series A-2 convertible preferred stock, par value $0.0001; zero and 26,342,102 shares authorized as of June 30, 2026 and December 31, 2025, respectively; zero and 26,342,102 shares issued and outstanding as of June 30, 2026 and December 31, 2025, respectively; liquidation preference of zero and $100,100 as of June 30, 2026 and December 31, 2025, respectively 99,757
Series B convertible preferred stock, par value $0.0001; zero and 47,578,938 shares authorized as of June 30, 2026 and December 31, 2025, respectively; zero and 47,578,934 shares issued and outstanding as of June 30, 2026 and December 31, 2025, respectively; liquidation preference of zero and $226,000 as of June 30, 2026 and December 31, 2025, respectively 225,571
Commitments and contingencies (Note 14)
Stockholders' deficit
Undesignated preferred stock, $0.0001 par value; 10,000,000 and zero shares authorized at June 30, 2026 and December 31, 2025, respectively; zero shares issued and outstanding at June 30, 2026 and December 31, 2025
Common stock, par value $0.0001; 700,000,000 and 159,070,000 shares authorized as of June 30, 2026 and December 31, 2025, respectively; 53,530,550 and 2,595,342 shares issued and outstanding as of June 30, 2026 and December 31, 2025, respectively 5 1
Additional paid-in capital 625,189 21,262
Accumulated other comprehensive income (475) 301
Accumulated deficit (202,117) (114,109)
Total stockholders' equity (deficit) 422,602 (92,545)
Total liabilities, convertible preferred stock and stockholders' equity (deficit) 441,681 249,009

Condensed Consolidated Statements of Cash Flows (Unaudited)

(In thousands)

Description Six months ended June 30, 2026 Six months ended June 30, 2025
Operating activities
Net loss (88,008) (28,202)
Adjustments to reconcile net loss to net cash used in operating activities:
Stock-based compensation expense 39,432 3,375
Depreciation expense 52 77
Amortization of operating lease right-of-use assets 656 592
Net amortization of premiums and discounts on investments (582) (2,019)
Changes in operating assets and liabilities:
Prepaid expenses and other current assets (433) (5,494)
Other non-current assets - (1,191)
Accounts payable 3,690 (2,604)
Related party payable (7) (283)
Accrued expenses and other current liabilities (461) 709
Operating lease liability (652) (490)
Net cash used in operating activities (46,313) (35,530)
Investing activities
Purchases of investments (300,652) (304,171)
Proceeds from maturities of investments 125,000 77,500
Purchases of property and equipment (323)
Net cash used in investing activities (175,652) (226,994)
Financing activities
Proceeds from initial public offering, net of underwriting discounts and commissions and deferred offering costs 239,338
Proceeds from exercise of stock options 807
Net cash provided by financing activities 240,145
Effect of exchange rates on cash and cash equivalents 1
Net increase (decrease) in cash and cash equivalents 18,181 (262,524)
Cash, cash equivalents, and restricted cash, beginning of period 46,496 309,553
Cash, cash equivalents, and restricted cash, end of period 64,677 47,029
Supplemental disclosure of non-cash operating, financing, and investing information:
Operating lease right-of-use assets obtained in exchange for lease liabilities 584 1,114
Deferred offering costs included in accounts payable and accrued expenses 97

Amounts as printed on the EDGAR/iXBRL face — (In thousands, except share and per share amounts); (In thousands). Labels, columns, and figures are the filing face, not a GAAP stencil. Interactive statements & notes on EDGAR ↗