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NASDAQ: PTGX Protagonist Therapeutics, Inc 10-Q

Protagonist swings to $162.8M Q2 profit on Takeda opt-out and ICOTYDE approval

Filed August 5, 2026 · Period ending June 30, 2026 · Compared to 10-Q Aug 6, 2025 · ~1 min read

Key Changes

  • high

    Revenue surged 3749.2% to $213.5M, driven by a $200M Takeda opt-out payment and a $50M JNJ milestone for ICOTYDE approval.

    MD&A: Operating results verify on EDGAR →
  • high

    Net income swung from a $34.8M loss to a $162.8M profit, with diluted EPS of $2.29.

    MD&A: Net income verify on EDGAR →
  • high

    ICOTYDE (icotrokinra) received FDA approval in March 2026 for moderate-to-severe plaque psoriasis, triggering a $50M milestone.

    MD&A: ICOTYDE approval verify on EDGAR →

2 more material changes behind this preview — plus the full narrative summary, section-by-section diffs against the prior filing, and verbatim quotes with EDGAR citations.

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Figures/quotes linked to EDGAR · Narrative written by AI · Aug 31, 2026 · How we verify