OTC: PKTX

ProtoKinetix, Inc.

CIK 0001128189 · SIC 2834 · Pharmaceutical Preparations

Micro Assets $483K as of Sep 13, 2026

ProtoKinetix, Incorporated (“ProtoKinetix,” “we,” “us,” “our,” or the “Company”) is a research and development stage bio-technology company focused on scientific medical research of AFGPs (Anti-Freeze Glycoproteins) or anti-aging glycoproteins, trademarked as AAGPs®. The Company has recently been… About this business →

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10-K Filed Sep 3, 2026 · Period ending Dec 31, 2025

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8-K Filed Jun 17, 2026 · Period ending Mar 31, 2026

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8-K Filed Nov 21, 2025 · Period ending Nov 21, 2025

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8-K Filed Nov 17, 2025 · Period ending Nov 13, 2025

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10-Q Filed Nov 13, 2025 · Period ending Sep 30, 2025

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8-K Filed Oct 10, 2025 · Period ending Oct 6, 2025

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10-Q Filed Aug 13, 2025 · Period ending Jun 30, 2025

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10-K Filed Mar 28, 2025 · Period ending Dec 31, 2024

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10-K Filed Mar 20, 2024 · Period ending Dec 31, 2023

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10-Q/A Filed Aug 20, 2012 · Period ending Jun 30, 2012

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10-K/A Filed Jan 24, 2011 · Period ending Dec 31, 2009

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Latest financial statements

From 10-K filed Sep 3, 2026 (period ending Dec 31, 2025). As printed on the EDGAR/iXBRL face — not generated by the model.

As filed

Statements of Operations

Description Years ended December 31, 2025 Years ended December 31, 2024
EXPENSES
Amortization intangible assets (Note 4) 51,292 52,870
General and administrative 58,135 61,470
Professional fees (Note 8) 177,610 144,806
Research and development 106,613 99,625
Share-based compensation (Note 5) 5,417
Operating Income (Expenses) (393,650) (364,188)
Net loss for the year (393,650) (364,188)
Net loss per common share (basic and diluted) (0.00) (0.00)
Weighted average number of common shares outstanding (basic and diluted) 386,284,947 358,557,930

Balance Sheets

Description As of December 31, 2025 As of December 31, 2024
ASSETS
Current Assets
Cash 1,118 (4,697)
Prepaid expenses and deposits (Note 3) 1,050 1,050
Total current assets 2,168 (3,647)
Intangible assets (Note 4) 481,206 469,784
Total assets 483,374 466,137
LIABILITIES AND STOCKHOLDERS' EQUITY
Current Liabilities
Accounts payable and accrued liabilities (Note 8) 185,434 124,047
Total liabilities 185,434 124,047
Stockholders' Equity
Common stock, $0.0000053 par value; 500,000,000 common shares authorized; 406,830,152 and 371,880,152 shares issued and outstanding for 2025 and 2024 respectively (Note 7) 2,177 1,987
Additional paid-in capital 48,917,559 48,568,249
Accumulated deficit (48,621,796) (48,228,146)
Total stockholders' equity 297,940 342,090
Total liabilities and stockholders' equity 483,374 466,137

Statements of Cash Flows

Description Years ended December 31, 2025 Years ended December 31, 2024
CASH FLOWS USED IN OPERATING ACTIVITIES
Net loss for the year (393,650) (364,188)
Adjustments to reconcile net loss to cash used in operating activities:
Amortization intangible assets 51,292 52,870
Fair value of compensatory options granted 5,417
Changes in operating assets and liabilities:
Prepaid expenses and deposits
Accounts payable and accrued liabilities 206,981 82,851
Net cash provided by (used in) operating activities (135,377) (223,050)
CASH FLOWS USED IN INVESTING ACTIVITIES
Purchase of intangible assets (56,308) (58,055)
Net cash used in investing activities (56,308) (58,055)
CASH FLOWS FROM FINANCING ACTIVITIES
Issuance of common stock for cash 197,500 256,000
Issuance of common stock for shareholder advance
Net cash from financing activities 197,500 256,000
Net change in cash 5,815 (25,105)
Cash, beginning of year (4,697) 20,408
Cash, end of year 1,118 (4,697)
Cash paid for interest
Cash paid for income taxes
Supplementary information – non-cash transactions:
Shares issued in exchange for consulting services and settlement of debt 152,000 9,000
Intangible asset costs remaining in account payable 23,840 17,434

Amounts as printed on the EDGAR/iXBRL face. Labels, columns, and figures are the filing face, not a GAAP stencil. Interactive statements & notes on EDGAR ↗

About ProtoKinetix, Inc.

Source: Item 1 (Business) from the 10-K filed September 3, 2026. Description as filed by the company with the SEC.

ITEM 1.
BUSINESS

ProtoKinetix, Incorporated (“ProtoKinetix,”
“we,” “us,” “our,” or the “Company”) is a research and development stage bio-technology
company focused on scientific medical research of AFGPs (Anti-Freeze Glycoproteins) or anti-aging glycoproteins, trademarked as AAGPs®.
The Company has recently been in the process of directing major efforts to the practical side of commercial validation. The commercial
applications for AAGPs® in large markets such as targeted health care solutions are numerous, and ProtoKinetix is currently
working with researchers, business leaders and advisors and commercial entities to bring AAGP® to market.

ProtoKinetix was incorporated as RJV Network,
Inc. under the laws of the State of Nevada on December 23, 1999 for the primary purpose of developing an internet-based listing site that
would provide detailed commercial real estate property listings and related data. In July 2003, the Company entered into an assignment
of license agreement with BioKinetix Research, Incorporated for the assignment of rights relating to proprietary technologies of BioKinetix
Research, Incorporated for the creation and commercialization of “superantibodies.” On July 8, 2003, the Company changed
its name to “ProtoKinetix, Incorporated.”

The Company’s executive (or corporate)
offices are located at 109 W Main St, Dalton, Ohio 44618. Our telephone number is (330) 445-4971 and our website is www.protokinetix.com.

Cautionary Note Regarding Forward-Looking
Statements

Read full description ↓

The information discussed in this Annual Report
on Form 10-K for the fiscal year ended December 31, 2025 as well as some statements in press releases and some oral statements of the
Company’s officers during presentations about the Company include “forward looking statements” within the meaning of
Section 27A of the Securities Act of 1933 (the “Securities Act”) and Section 21E of the Securities Exchange Act of 1934 (the
“Exchange Act”). All statements, other than statements of historical facts, included herein and therein concerning,
among other things, planned capital expenditures, future cash flows and borrowings, pursuit of potential acquisition opportunities, our
financial position, business strategy and other plans and objectives for future operations, are forward looking statements. These forward
looking statements are identified by their use of terms and phrases such as “may,” “expect,” “estimate,”
“project,” “plan,” “believe,” “intend,” “achievable,” “anticipate,”
“will,” “continue,” “potential,” “should,” “could,” and similar terms and
phrases. Although we believe that the expectations reflected in these forward-looking statements are reasonable, they do involve
certain assumptions, risks and uncertainties and are not (and should not considered to be) guarantees of future performance. Our results
could differ materially from those anticipated in these forward-looking statements as a result of certain factors, including, among others:


Our capital requirements and the uncertainty of being able to obtain additional funding on terms acceptable to us;


Our plans to develop and commercialize products from the AAGP® molecule;


Ongoing testing of the AAGP® molecule;


Our intellectual property position;


Our commercialization, marketing and manufacturing capabilities and strategy;


Our ability to retain key members of our senior management and key scientific consultants;


The effects of competition;


Our potential tax liabilities resulting from conducting business in the United States and Canada;


The effect of further sales or issuances of our common stock and the price and volume volatility of our common stock; and our common stock’s limited trading history.

3

Finally, our future results will depend upon various
other risks and uncertainties, including, but not limited to, those detailed in the section entitled “Risk Factors” included
elsewhere in this Annual Report. All forward looking statements attributable to us or persons acting on our behalf are expressly
qualified in their entirety by the cautionary statements in this section and elsewhere in this Annual Report. Other than as required
under securities laws, we do not assume a duty to update these forward looking statements, whether as a result of new information, subsequent
events or circumstances, changes in expectations or otherwise.

Recent Developments

On June 6, 2023,
the Company announced the submission of a research paper describing cell characterization, graft evaluation, and yield of islet-like cells
differentiated from patient-derived iPSCS for the treatment and eventual cure of Type-1 Diabetes for publication in Transplantation.

Research and Development

Our business depends on our ability to sponsor research
and development activities. For the year ended December 31, 2025, the Company incurred total research and development expenses of
$106,613 (2024 - $99,625). In order to reach the Company’s goals of developing a marketable product, we will need to increase
the funding of our research and development activities which at this time is limited by our ability to raise money to fund the Company.