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NASDAQ: ORKA Oruka Therapeutics, Inc. 10-Q

Net loss widens 68% to -$41.2M in Q2 2026 as R&D spend rises

Filed August 10, 2026 · Period ending June 30, 2026 · Compared to 10-Q Aug 11, 2025 · ~2 min read

Key Changes

  • high

    Net loss for Q2 2026 was $41.2M, up 68% from $24.6M a year earlier, as R&D expenses rose 65% to $72.4M for the six months. Operating loss widened 76% YoY to $50.1M. The company is burning cash faster to support multiple Phase 2 trials.

    MD&A: Operating Results verify on EDGAR →
  • high

    Cash and marketable securities reached $1.1B as of June 30, 2026, up from $351.5M a year earlier. In July 2026, the company raised an additional $122.5M via the ATM.

    Notes: Subsequent Events verify on EDGAR →
  • high

    ORKA-001 Phase 2a (EVERLAST-A) Week 16 data showed 63.5% of participants achieved complete skin clearance (PASI 100), with 83% achieving PASI 90. Phase 2b (EVERLAST-B) enrolled 187 patients; Week 16 data expected Q4 2026. Phase 3 initiation planned for H1 2027.

    MD&A: Clinical Programs verify on EDGAR →

2 more material changes behind this preview — plus the full narrative summary, section-by-section diffs against the prior filing, and verbatim quotes with EDGAR citations.

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Figures/quotes linked to EDGAR · Narrative written by AI · Aug 26, 2026 · How we verify